1000g – linkstream2 microblog

Hum Genet. 2012 Oct 10. Ostrer H, Skorecki K. Departments of Pathology and Genetics, Albert Einstein College of Medicine, Bronx, NY, 10461, USA. http://www.ncbi.nlm.nih.gov/pubmed/23052947 Admixture...

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Non-coding variation review

November 24, 2012, 6:51 pm

http://www.nature.com/nbt/journal/v30/n11/full/nbt.2422.html

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Comment on “Evidence of Abundant Purifying Selection in Humans for Recently...

May 17, 2013, 10:47 pm

http://www.sciencemag.org/content/340/6133/682.1.full

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Genome-wide inference of natural selection on human transcription factor...

June 9, 2013, 8:40 pm

http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.2658.html Uses only CG data for variation, only TFBS data form ENCODE. QT:”the binding sites of several transcription factors show clear evidence...

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Q&A: David Altshuler on How to Share Millions of Human Genomes – ScienceInsider

June 10, 2013, 7:04 pm

http://news.sciencemag.org/scienceinsider/2013/06/-qa-david-altshuler-on-how-to-sh.html But how will a little player participate in this? MT @gtyrelle: Q&A: on How to Share Millions of Human...

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Gene intolerance scores in a Plos Gen paper

August 26, 2013, 1:23 pm

http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1003709#pgen-1003709-g006 This paper discusses gene intolerance score — very similar to depletion of common polymorphisms. They...

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PacBio data for CHM1 genome

October 23, 2013, 7:58 pm

It look as though the data are now ready for download http://datasets.pacb.com/2013/Human10x/READS/index.html along with a brief description of the data...

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1000 Genomes Selection Browser 1.0: a genome browser dedicated to signatures...

December 1, 2013, 1:21 pm

Looks useful! http://nar.oxfordjournals.org/content/early/2013/11/24/nar.gkt1188

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amino acid changes in 1000 Genomes Project Thornton Lab

June 23, 2014, 2:26 pm

1000G v disease variants http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1003382

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Million Veteran Program (MVP)

June 24, 2014, 3:35 pm

http://www.research.va.gov/MVP/ Principal Investigators : John Concato, M.D., M.S., M.P.H. Yale J. Michael Gaziano, M.D., M.P.H. Harvard QT:{{“ It’s Launch Time for the Million Veteran Program… The VA...

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The genomic landscape of Neanderthal ancestry in present-day humans : Nature...

October 31, 2014, 10:26 pm

The genomic landscape of #Neanderthal ancestry in…humans http://www.nature.com/nature/journal/v507/n7492/full/nature12961.html Regions enriched & depleted in ancient alleles, from 1000G 1004 indiv....

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No evidence that selection has been less effective at removing deleterious...

January 17, 2015, 9:43 pm

Removing deleterious mutations in Europeans [v] Africans http://www.nature.com/ng/journal/vaop/ncurrent/full/ng.3186.html Comparing nonsynonymous freq. betw. populations HT @obahcall

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The fine-scale genetic structure of the British population : Nature : Nature...

July 10, 2015, 10:34 pm

The fine-scale genetic structure of the British population http://www.nature.com/nature/journal/v519/n7543/full/nature14230.html Correlation w. geography, reflecting Anglo-Saxon migration...

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